Article
Association of CLCNKB haplotypes and hypertension in Mongolian and Han populations.
Clinical and experimental hypertension (New York, N.Y. : 1993) - 1 Jan 2012
Su Xiulan, Chang Peiye, Liu Zhiyue, Yan Meirong, Liu Guirong, Cui Hongwei
Abstract excerpt
We investigated a possible association between genetic variations in chloride channel Kb (CLCNKB) gene and essential hypertension (EH) in the Mongolian and Han populations in Inner Mongolia. Our study included 414 unrelated Mongolian herdsmen and 524 Han farmers. Two tagSNPs of CLCNKB (rs945393 and rs10803414) were identified from the Chinese HapMap database based on pairwise r(2) ≥ 0.5 and minor allele frequency...
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