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Article

Activation of self-reactive B cells and autoimmune diseases.

Reviews in immunogenetics - 1 Jan 2000

Burrows P D, Suematsu S, Watanabe T

Abstract excerpt

The development of antigen-specific cells of the immune system, the T and B lymphocytes, creates a dilemma. On the one hand, survival of the organism depends upon the generation of a nearly limitless repertoire of potential antigen-binding specificities so that cells able to respond to pathogens are present prior to contact. However, by devising genetic strategies to maximize receptor diversity, the generation of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 11324692

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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