Article
Expression and localisation of the pyrophosphate transporter, ANK, in murine kidney cells.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2007
Carr Georgina, Sayer John A, Simmons Nicholas L
Abstract excerpt
BACKGROUND/AIMS: Mutation of the pyrophosphate transporter, ANK, results in progressive arthritis in mice. ANK is expressed in non-skeletal tissues including kidney. The aim was therefore to investigate ANK location at the cellular and subcellular level in renal cells. METHODS: RT-PCR identified a murine cell-line, mIMCD3, expressing ANK. The intra-renal distribution of ANK was determined by immunohistochemistry...
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