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Article

Extracellular pyrophosphate in the kidney: how does it get there and what does it do?.

Nephron. Physiology - 1 Jan 2012

Moochhala Shabbir H

Abstract excerpt

Pyrophosphate (PPi) is well known as a regulator of calcification, and the ANKH (ANK in mouse) protein has a role in the membrane transport of PPi. Earlier work concentrated on bones and joints, but ANKH is also likely to have important roles in the kidney, with newer studies focusing on vascular calcification in renal failure. Renal calcification can occur due to a naturally occurring ANK mouse mutation, yet...

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Identifiers

PMID: 23075758
DOI: 10.1159/000341597
PMCID: PMC5166521

Genes

ANKH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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