Article
Onco-suppressor genes and their involvement in cancer (review).
Anticancer research - 1 Jan 2000
Anderson M L, Spandidos D A
Abstract excerpt
Onco-suppressor genes are a heterogeneous set of genes that inhibit the cancer-related phenotype of cells. Because they are difficult to identify, only a few have been described. Evidence for their existence has mainly been indirect and comes from the following types of study. 1. Recessive cancer genes in higher and lower eukaryotes have been detected. If both alleles of these genes are deleted or inactivated,...
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