Article
Transcriptional activation analysis of oncogene function.
Methods in enzymology - 1 Jan 1994
Hauser C A, Der C J, Cox A D
Abstract excerpt
Because no single assay provides a complete analysis of the transformed phenotype, transactivation assays complement the cell growth and tumorigenicity analyses of oncogene function. Transactivation of ORE-containing genes is such a common feature of a diverse variety of viral and cellular oncoge...
Topics
- 3T3 Cells
- Animals
- Cell Division
- Cell Transformation, Neoplastic
- GTP-Binding Protein alpha Subunit, Gi2
- GTP-Binding Protein alpha Subunits, Gi-Go
- GTP-Binding Proteins
- Gene Expression Regulation
- Macromolecular Substances
- Mice
- Oncogenes
- Phenotype
- Promoter Regions, Genetic
- Proto-Oncogene Proteins
- Proto-Oncogenes
- Recombinant Proteins
- Regulatory Sequences, Nucleic Acid
- Transcription, Genetic