Article
How do mutated oncogenes and tumor suppressor genes cause cancer?
Medical oncology (Northwood, London, England) - 1 Apr 1998
Grandér D
Abstract excerpt
In recent decades we have been given insight into the process that transforms a normal cell into a malignant cancer cell. It has been recognised that malignant transformation occurs through successive mutations in specific cellular genes, leading to the activation of oncogenes and inactivation of...
Topics
- Gene Expression Regulation, Neoplastic
- Genes, Tumor Suppressor
- Humans
- Mutation
- Neoplasms
- Oncogenes