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Article

Matrix metalloproteinase-9 polymorphisms and renal cell carcinoma in a Japanese population.

Cancer letters - 8 Sept 2006

Awakura Yasuo, Ito Noriyuki, Nakamura Eijiro, Takahashi Takeshi, Kotani Hirokazu, Mikami Yoshiki, Manabe Toshiyuki, Kamoto Toshiyuki, Habuchi Tomonori, Ogawa Osamu

Abstract excerpt

Matrix metalloproteinase-9 (MMP-9) plays a pivotal role in cancer invasion and metastasis. Recently, experimental study has shown that MMP-9 is also implicated in early carcinogenesis. We hypothesized that MMP-9 polymorphisms influence the predisposition to develop renal cell carcinoma (RCC). To test the hypothesis, we determined MMP-9 C-1562T and R279Q genotypes in Japanese RCC cases (n=179) and controls...

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Source

Identifiers

PMID: 16466849
DOI: 10.1016/j.canlet.2005.10.005

Genes

MMP9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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