Article
Association of matrix metalloproteinases 1, 7, and 9 gene polymorphisms with genetic susceptibility to colorectal carcinoma in a Han Chinese population.
DNA and cell biology - 1 Nov 2010
Fang Wen-Liang, Liang Wei-Bo, He Huan, Zhu Yi, Li Shi-Liu, Gao Lin-Bo, Zhang Lin
Abstract excerpt
Matrix metalloproteinases (MMPs) play an important role in colorectal cancer (CRC). Accumulated evidence suggests an association between MMP-1, MMP-7, and MMP-9 functional gene polymorphisms with several tumors. The aim of this study was to investigate the association of single-nucleotide polymorphism (SNP) at MMP-1 16071G/2G, MMP-7 181A/G, and MMP-9 279R/Q genes with CRC in the southwest Chinese Han population....
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