Article
Association of Matrix Metalloproteinase-9 rs3918242 Promoter Genotypes With Colorectal Cancer Risk.
Anticancer research - 1 Dec 2019
Wu Ming-Hsien, Tzeng Huey-En, Wu Cheng-Nan, Yueh Te-Cheng, Peng Yen-Chun, Tsai Chun-Hao, Wang Yun-Chi, Ke Tao-Wei, Pei Jen-Sheng, Chang Wen-Shin, Tsai Chia-Wen, Bau DA-Tian
Abstract excerpt
BACKGROUND/AIM: Matrix metalloproteinase-9 (MMP-9) is responsible for modifying extracellular components and plays a crucial role in the metastatic behavior of cancer. This study aimed at examining the role of MMP-9 rs3918242 genotypes on colorectal cancer (CRC) risk. MATERIALS AND METHODS: A total of 362 CRC patients and 362 healthy subjects in Taiwan, were examined by the polymerase chain reaction-restriction...
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