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Article

Putative functional polymorphisms of MMP9 predict survival of NSCLC in a Chinese population.

International journal of cancer - 1 May 2009

Jin Guangfu, Miao Ruifen, Hu Zhibin, Xu Lin, Huang Xinen, Chen Yijiang, Tian Tian, Wei Qingyi, Boffetta Paolo, Shen Hongbing

Abstract excerpt

Matrix metalloproteinases (MMPs) play a crucial role in cancer progression and their over-expression is often associated with unfavorable survival of non-small cell lung cancer (NSCLC). Because genetic variants can alter expression level or biological activity of MMPs, we hypothesized that potentially functional single nucleotide polymorphisms (SNPs) in key MMP genes may be associated with the survival of NSCLC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19132754
DOI: 10.1002/ijc.24190

Genes

MMP9
MMP1
MMP12
MMP2
MMP3
MMP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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