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Article

G>C SNP of thymidylate synthase with respect to colorectal cancer.

Pharmacogenomics - 1 Aug 2007

Gusella Milena, Padrini Roberto

Abstract excerpt

Several studies indicate that low thymidylate synthase (TS) protein levels in tumor and normal tissues of colorectal cancer patients are associated with better clinical response to fluorouracil-based chemotherapy and higher risk of toxicity. However, no correlation or even reverse correlation has also been reported. These conflicting results may be partly due to the methodological limitations of the...

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PMID: 17716232
DOI: 10.2217/14622416.8.8.985

Genes

TYMS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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