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Article

Relationships between promoter polymorphisms in the thymidylate synthase gene and mRNA levels in colorectal cancers.

European journal of cancer (Oxford, England : 1990) - 1 Sept 2005

Morganti Maria, Ciantelli Monica, Giglioni Beatrice, Putignano Anna L, Nobili Stefania, Papi Laura, Landini Ida, Napoli Cristina, Valanzano Rosa, Cianchi Fabio, Boddi Vieri, Tonelli Francesco, Cortesini Camillo, Mazzei Teresita, Genuardi Maurizio, Mini Enrico

Abstract excerpt

Thymidylate synthase (TS) intratumoural expression may be a prognostic marker and predict outcome of 5-fluorouracil (5-FU)-based chemotherapy in colorectal cancer patients. The TS gene promoter enhancer region contains two different polymorphisms which can influence TS mRNA transcriptional and tr...

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Identifiers

PMID: 16182121
DOI: 10.1016/j.ejca.2005.06.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-16182121-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Relationships between promoter polymorphisms in the thymidylate synthase gene and mRNA levels in colorectal cancers.PMID 16182121Read ↗

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