Article
Enhanced B-Raf protein expression is independent of V600E mutant status in thyroid carcinomas.
Human pathology - 1 Dec 2007
Kondo Tetsuo, Nakazawa Tadao, Murata Shin-ichi, Kurebayashi Junichi, Ezzat Shereen, Asa Sylvia L, Katoh Ryohei
Abstract excerpt
BRAF (7q24) encodes a serine/threonine protein kinase, and its expression level varies in different tissues. Although a high prevalence of BRAF mutation has been suggested as an important event in thyroid tumorigenesis, little is known about the expression pattern of B-Raf in the thyroid. Thus, we examined the expression of B-Raf in various neoplastic and nonneoplastic thyroid tissues and compared it with BRAF...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
