Article
B-Raf mutation: a key player in molecular biology of cancer.
Experimental and molecular pathology - 1 Dec 2013
Rahman M A, Salajegheh A, Smith R A, Lam A K-Y
Abstract excerpt
B-Raf is one of the more commonly mutated proto-oncogenes implicated in the development of cancers. In this review, we consider the mechanisms and clinical impacts of B-Raf mutations in cancer and discuss the implications for the patient in melanoma, thyroid cancer and colorectal cancer, where B-Raf mutations are particularly common.
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