Article
High prevalence of B-RAF mutation in papillary carcinoma of the thyroid in north-east Italy.
International journal of surgical pathology - 1 Jun 2010
Girlando Salvatore, Cuorvo Lucia Veronica, Bonzanini Mariella, Morelli Luca, Amadori Pierluigi, Dalla Palma Paolo, Barbareschi Mattia
Abstract excerpt
B-RAF V600E mutation is frequently observed in several tumors, including papillary thyroid carcinomas (PTCs), where it is considered of potential diagnostic and prognostic value. The reported prevalence of B-RAF mutation in PTCs in different Italian populations varies from 14% to 69%. The authors investigate the prevalence and utility of the B-RAF V600E mutation in a series of 91 fine needle aspiration biopsies...
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