Article
Declining prevalence of HIV-1 drug resistance in treatment-failing patients: a clinical cohort study.
Antiviral therapy - 1 Jan 2007
Di Giambenedetto Simona, Bracciale Laura, Colafigli Manuela, Colatigli Manuela, Cattani Paola, Pinnetti Carmen, Pannetti Carmen, Bacarelli Alessandro, Prosperi Mattia, Fadda Giovanni, Cauda Roberto, De Luca Andrea
Abstract excerpt
OBJECTIVES: A major barrier to successful viral suppression in HIV type 1 (HIV-1)-infected individuals is the emergence of virus resistant to antiretroviral drugs. We explored the evolution of genotypic drug resistance prevalence in treatment-failing patients from 1999 to 2005 in a clinical cohort. PATIENTS AND METHODS: Prevalence of major International AIDS Society-USA HIV-1 drug resistance mutations was...
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