Article
Effects of drug resistance on viral load in patients failing antiretroviral therapy.
Journal of medical virology - 1 May 2006
Machouf N, Thomas R, Nguyen V K, Trottier B, Boulassel M R, Wainberg M A, Routy J P
Abstract excerpt
Previous studies on patients who develop drug resistant HIV-1 variants have shown that continued use of failing regimens might provide clinical benefit. However, the effect of long-term exposure to drug resistant variants may lead to emergence of compensatory mutations that may jeopardize this effect. In this study, we assess associations among type and number of drug resistant mutations, viral load and disease...
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