Article
Evolving patterns of HIV-1 resistance to antiretroviral agents in newly infected individuals.
AIDS (London, England) - 26 Jul 2002
Simon Viviana, Vanderhoeven Jeroen, Hurley Arlene, Ramratnam Bharat, Louie Michael, Dawson Keith, Parkin Neil, Boden Daniel, Markowitz Martin
Abstract excerpt
OBJECTIVE: To assess temporal changes in prevalence of transmitted HIV-1 drug resistance in a homogeneous cohort of newly infected individuals. METHODS: Pretreatment genotypic and phenotypic drug resistance was tested in 154 subjects with primary HIV-1 infection identified between 1995 and 2001 (group A; n = 76) and 1999 and 2001 (group B; n = 78). Sequence analysis was assessed by population-based sequencing....
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