Article
HIV-1 drug-resistance patterns among patients on failing treatment in a large number of European countries.
Acta dermatovenerologica Alpina, Pannonica, et Adriatica - 1 Dec 2010
van de Vijver D A M C, Wensing A M J, Åsjö B, Bruckova M, Jorgensen L B, Camacho R, Horban A, Linka M, Lazanas M, Loveday C, MacRae E, Nielsen C, Paraskevis D, Poljak M, Puchhammer-Stöckl E, Ruiz L, Schmit J-C, Stanczak G, Stanojevic M, Vandamme A-M, Vercauteren J, Zazzi M, Bacheler L, Lecocq P, Villacian J, Boucher C A B
Abstract excerpt
BACKGROUND: Information about patterns of HIV-1 drug resistance among treatment-exposed patients is crucial for the development of novel effective drugs. Currently no system exists that monitors patterns of resistance in patients failing therapy. METHODS: The study included 1,988 HIV-1 sequences from patients experiencing therapy failure collected between 2000 and 2004 in 15 European countries. Genotypic...
Topics
- Adult
- Amino Acid Substitution
- Drug Resistance, Viral
- Europe
- Female
- Genotype
- HIV Infections
- HIV Protease
- HIV Protease Inhibitors