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Article

Microsomal epoxide hydrolase, glutathione S-transferase P1, traffic and childhood asthma.

Thorax - 1 Dec 2007

Salam Muhammad T, Lin Pi-Chu, Avol Edward L, Gauderman W James, Gilliland Frank D

Abstract excerpt

BACKGROUND: Microsomal epoxide hydrolase (EPHX1) metabolises xenobiotics including polyaromatic hydrocarbons (PAHs). Functional variants at this locus have been associated with respiratory diseases. The effects of EPHX1 variants may depend upon exposures from tobacco smoke and traffic emissions that contain PAHs as well as variants in other enzymes in the PAH metabolic pathway such as glutathione S-transferase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17711870
DOI: 10.1136/thx.2007.080127
PMCID: PMC2094290

Genes

EPHX1
GSTP1
GSTM1
GSTT1
PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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