Article
Air pollution and childhood bronchitis: Interaction with xenobiotic, immune regulatory and DNA repair genes.
Environment international - 1 Feb 2016
Ghosh Rakesh, Rossner Pavel, Honkova Katerina, Dostal Miroslav, Sram Radim J, Hertz-Picciotto Irva
Abstract excerpt
BACKGROUND: Gene-environment interactions have been investigated for diseases such as asthma, chronic obstructive pulmonary disease, cancer etc. but acute disease like bronchitis has rarely been studied. We investigated interactions between air pollution (polycyclic aromatic hydrocarbons (PAH) and particulate matter <2.5 μm (PM2.5)) and single nucleotide polymorphisms (SNP) in EPHX1, IL10, STAT4 and XPC genes in...
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