Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Parental smoking and risk of childhood brain tumors by functional polymorphisms in polycyclic aromatic hydrocarbon metabolism genes.

PloS one - 1 Jan 2013

Barrington-Trimis Jessica L, Searles Nielsen Susan, Preston-Martin Susan, Gauderman W James, Holly Elizabeth A, Farin Federico M, Mueller Beth A, McKean-Cowdin Roberta

Abstract excerpt

BACKGROUND: A recent meta-analysis suggested an association between exposure to paternal smoking during pregnancy and childhood brain tumor risk, but no studies have evaluated whether this association differs by polymorphisms in genes that metabolize tobacco-smoke chemicals. METHODS: We assessed 9 functional polymorphisms in 6 genes that affect the metabolism of polycyclic aromatic hydrocarbons (PAH) to evaluate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Follow-Up Studies

Share to Infant

Share to Maternal Exposure

Share to Polycyclic Aromatic Hydrocarbons

Share to Pregnancy

Share to Smoking

Source

Open in PubMed Open full text

Identifiers

PMID: 24260161
DOI: 10.1371/journal.pone.0079110
PMCID: PMC3832498

Genes

PAH
EPHX1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Parental smoking and risk of childhood brain tumors by functional polymorphisms in polycyclic aromatic hydrocarbon metabolism genes.PMID 24260161Read ↗

Air pollutants, genes and early childhood acute bronchitis.Semantic proximity Read ↗

Maternal variation in EPHX1, a xenobiotic metabolism gene, is associated with childhood medulloblastoma: an exploratory case-parent triad study.Semantic proximity Read ↗

Parental Exposure to Polycyclic Aromatic Hydrocarbons and the Risk of Childhood Brain Tumors: The SEARCH International Childhood Brain Tumor StudySemantic proximity Read ↗

Variation in genes relevant to aromatic hydrocarbon metabolism and the risk of adult brain tumors.Semantic proximity Read ↗

Significant interactions between maternal PAH exposure and single nucleotide polymorphisms in candidate genes on B[ a ]P-DNA adducts in a cohort of non-smoking Polish mothers and newborns.Semantic proximity Read ↗

An exploratory case-only analysis of gene-hazardous air pollutant interactions and the risk of childhood medulloblastoma.Semantic proximity Read ↗

Environmental carcinogens disproportionally mutate genes implicated in neurodevelopmental disordersSemantic proximity Read ↗

Indoor air pollution and neural tube defects: effect modification by maternal genes.Semantic proximity Read ↗

Effect of gene-environment Interactions on mental development in African American, Dominican, and Caucasian mothers and newborns.Semantic proximity Read ↗

Molecular epidemiologic research on the effects of environmental pollutants on the fetus.Semantic proximity Read ↗

Prenatal Polycyclic Aromatic Hydrocarbon Exposure Leads to Behavioral Deficits and Downregulation of Receptor Tyrosine Kinase, METSemantic proximity Read ↗

Maternal genetic polymorphisms of phase II metabolic enzymes and the risk of fetal neural tube defects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.