Article
Allele-Specific DNA Methylation Detection by Pyrosequencing®.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2015
Kristensen Lasse Sommer, Johansen Jens Vilstrup, Grønbæk Kirsten
Abstract excerpt
DNA methylation is an epigenetic modification that plays important roles in healthy as well as diseased cells, by influencing the transcription of genes. In spite the fact that human somatic cells are diploid, most of the currently available methods for the study of DNA methylation do not provide information on the methylation status of individual alleles of genes. This information may be of importance in many...
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