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Article

Monitoring methylation changes in cancer.

Advances in biochemical engineering/biotechnology - 1 Jan 2007

Beier Verena, Mund Cora, Hoheisel Jörg D

Abstract excerpt

Methylation of cytosines at their carbon-5 position plays an important role both during development and in tumorgenesis. The methylation occurs almost exclusively in CpG dinucleotides. While the bulk of human genomic DNA is depleted in CpG sites, there are CpG-rich stretches, so-called CpG islands, which are located in promoter regions of more than 70% of all known human genes. In normal cells, CpG islands are...

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PMID: 17290816
DOI: 10.1007/10_024

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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