Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Tumor necrosis factor-alpha gene polymorphism correlates with cardiovascular disease in patients with end-stage renal disease.

Molecular diagnosis & therapy - 1 Jan 2007

Buraczynska Monika, Mierzicki Piotr, Buraczynska Kinga, Dragan Michał, Ksiazek Andrzej

Abstract excerpt

BACKGROUND AND OBJECTIVE: Tumor necrosis factor-alpha (TNFalpha) is a potent proinflammatory cytokine. Through its effects on lipid metabolism and endothelial function, TNFalpha is involved in cardiovascular disease (CVD). We have studied two polymorphisms in the promoter region of the TNFalpha gene (TNF -308G/A and TNF -238G/A) in end-stage renal disease (ESRD) patients with and without CVD. The aim was to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Diseases
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genotype

Share to Kidney Failure, Chronic

Share to Polymorphism, Single Nucleotide

Share to Renal Dialysis

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 17705580
DOI: 10.1007/BF03256247

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Tumor necrosis factor-alpha gene polymorphism correlates with cardiovascular disease in patients with end-stage renal disease.PMID 17705580Read ↗

Association of TNF-α -308 G > A and ACE I/D gene polymorphisms in hemodialysis patients with arteriovenous fistula thrombosis.Semantic proximity Read ↗

Association of tumour necrosis factor-α polymorphism in patients with end stage renal disease.Semantic proximity Read ↗

Correlation between a gene polymorphism of tumor necrosis factor-alpha (G/A) and end-stage renal disease: a pilot study from north India.Semantic proximity Read ↗

TNF alpha-308 genotype and renin-angiotensin system in hemodialysis patients: an effect on inflammatory cytokine levels?Semantic proximity Read ↗

Monocyte chemoattractant protein-1 (MCP-1) gene polymorphism as a potential risk factor for cardiovascular disease in hemodialyzed patients.Semantic proximity Read ↗

Tumor necrosis factor-alpha -308 gene polymorphism is associated with synthetic hemodialysis graft failure.Semantic proximity Read ↗

Transforming growth factor-beta 1 gene polymorphisms and cardiovascular disease in hemodialysis patients.Semantic proximity Read ↗

Cardiovascular disease in kidney transplant recipients: the prognostic value of inflammatory cytokine genotypes.Semantic proximity Read ↗

Association of the tumour necrosis factor alpha -308G/A polymorphism with the risk of diabetes in an elderly population-based cohort.Semantic proximity Read ↗

Tumornecrosis-factor-α 308 GA polymorphism in atherosclerotic patients.Semantic proximity Read ↗

A variant of position -308 of the Tumour necrosis factor alpha gene promoter and the risk of coronary heart disease.Semantic proximity Read ↗

A polymorphism in the promoter of the tumor necrosis factor-alpha gene (-308) is associated with coronary heart disease in type 2 diabetic patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.