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Article

Tumor necrosis factor-alpha -308 gene polymorphism is associated with synthetic hemodialysis graft failure.

Journal of investigative medicine : the official publication of the American Federation for Clinical Research - 1 Feb 2003

Ram Sunanda, Bass Kristen, Abreo Ken, Baier R John, Kruger Thomas E

Abstract excerpt

BACKGROUND: Progressive venous stenosis mediated, in part, by inflammatory cytokines is a major cause of synthetic hemodialysis graft failure. A tumor necrosis factor-alpha (TNF-alpha) gene polymorphism (G to A, position -308) has been shown to increase plasma cytokine levels and severity of diseases with an underlying inflammatory component. METHODS: We genotyped 67 patients with synthetic...

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PMID: 12580317
DOI: 10.2310/6650.2003.33522

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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