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Association of tumour necrosis factor-α polymorphism in patients with end stage renal disease.

Nephrology (Carlton, Vic.) - 1 Jun 2015

Singh Kamini, Prasad Kashi Nath, Mishra Priyanka, Singh Satyendra Kumar, Kharwar Nagendra Kumar, Prasad Narayan, Gupta Amit, Srivastava Janmejai Kumar

Abstract excerpt

AIM: Cytokines play a critical role in the pathophysiology of end stage renal disease (ESRD). Tumour necrosis factor-a (TNF-α) is an important cytokine involved in initiation and progression of renal diseases. The present study evaluated the association of specific alleles/genotype of TNF-α with chronic renal failure (CRF) and ESRD. METHODS: A total of 30 CRF patients who were not on renal replacement therapy, 85...

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PMID: 25589331
DOI: 10.1111/nep.12398

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TNF

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