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Article

Correlation between a gene polymorphism of tumor necrosis factor-alpha (G/A) and end-stage renal disease: a pilot study from north India.

Clinica chimica acta; international journal of clinical chemistry - 1 Aug 2006

Manchanda Parmeet Kaur, Kumar Anant, Kaul Anupma, Mittal Rama Devi

Abstract excerpt

BACKGROUND: Patients with chronic kidney disease manifest an inflammatory state in comparison to healthy individuals. Tumor necrosis factor-alpha (TNF-alpha) is a potent pro-inflammatory cytokine involved in initiation and progression of renal injury. We examined the 2-promoter region polymorphism of TNF-alpha gene G to A at -308 and at +488 sites in end-stage renal disease (ESRD) subjects. METHODS: The TNF-alpha...

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PMID: 16545788
DOI: 10.1016/j.cca.2006.02.002

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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