Article
Genetic association of a polymorphism of the cAMP-responsive element binding protein-binding protein with steroid-induced osteonecrosis after kidney transplantation.
Journal of bone and mineral metabolism - 1 Jan 2007
Tamura Kyoko, Nakajima Shigeo, Hirota Yoshio, Takahashi Kenji A, Fujioka Mikihiro, Kubo Toshikazu, Iwatani Yoshinori, Ozono Keiichi
Abstract excerpt
Nontraumatic osteonecrosis (ON) of the femoral head is known to be one of the major complications after organ transplantations. Although the precise mechanism is still uncertain, the administration of glucocorticoid (GC) has been considered to play an important role in the occurrence of ON. To elucidate the genetic factors involved in this pathogenesis, we analyzed single nucleotide polymorphisms (SNP) in the...
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