Article
Association of ABCB1/MDR1 polymorphisms in patients with glucocorticoid-induced osteonecrosis of the femoral head: Evidence for a meta-analysis.
Gene - 10 Sept 2015
Zhou Zifei, Hua Yingqi, Liu Junjian, Zuo Dongqing, Wang Hongsheng, Chen Quanchi, Zheng Longpo, Cai Zhengdong
Abstract excerpt
PURPOSE: Glucocorticoid-induced osteonecrosis of the femoral head (GC-induced ONFH) is a rebarbative disease affecting people from all ages, especially young adults, and often leads to severe joint pain and limitations on physical activity. Numerous studies have reported that ABCB1 polymorphisms are associated with GC-induced ONFH, but the results are inconclusive, partially because the sample size of published...
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