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Article

Genetic association of the P-glycoprotein gene ABCB1 polymorphisms with the risk for steroid-induced osteonecrosis of the femoral head in Chinese population.

Molecular biology reports - 1 May 2014

Zhang Yanqiong, Kong Xiangying, Wang Rongtian, Li Shangzhu, Niu Yanfang, Zhu Liuluan, Chen Weiheng, Lin Na

Abstract excerpt

Steroid administration, which is commonly performed for the treatment of autoimmune inflammatory diseases, cancers or organ transplantation, has been a leading cause of nontraumatic osteonecrosis of the femoral head (ONFH). Single nucleotide polymorphisms (SNPs) of the adenosine triphosphate-binding cassette B1 (ABCB1) gene have been demonstrated to be related to steroid-induced ONFH in small sample sizes of...

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Identifiers

PMID: 24469730
DOI: 10.1007/s11033-014-3173-y

Genes

ABCB1

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