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Article

Glucocorticoid Receptor Gene Polymorphisms and Femoral Head Osteonecrosis.

Medicina (Kaunas, Lithuania) - 31 May 2026

Liu De-Yi, Lai I-Chang, Ku Nien-En, Hsu Chang-Yuan, Wang Chu-Ching, Hsu Shih-Chan, Ko Jih-Yang, Kuo Shu-Jui

Abstract excerpt

Background and Objectives: Non-traumatic osteonecrosis of the femoral head (ONFH) is a multifactorial disorder influenced by both environmental and genetic factors. The nuclear receptor subfamily 3 group C member 1 (NR3C1) gene encodes the glucocorticoid receptor, which plays a key role in bone metabolism, vascular regulation, and stress response. This study aimed to investigate the association between NR3C1...

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Identifiers

PMID: 42356081
DOI: 10.3390/medicina62061068
PMCID: PMC13303425

Genes

NR3C1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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