Article
ABCB1 C3435T and G2677T/A polymorphism decreased the risk for steroid-induced osteonecrosis of the femoral head after kidney transplantation.
Pharmacogenetics - 1 Nov 2003
Asano Takeshi, Takahashi Kenji A, Fujioka Mikihiro, Inoue Shigehiro, Okamoto Masahiko, Sugioka Nobuyuki, Nishino Hoyoku, Tanaka Takashi, Hirota Yoshio, Kubo Toshikazu
Abstract excerpt
Advances in transplantation technology have brought about great benefits to patients suffering from organ failure, but the problem still remains of complications induced by steroids used for post-transplant immunosuppression. Among the side-effects caused by steroids, non-traumatic osteonecrosis of the femoral head (ONF) constitutes a serious problem. The same protocol for steroid administration induces ONF in...
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