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Article

Clinical Value of ABCB1 and PAI-1 Gene Polymorphisms in Predicting Glucocorticoid-induced Adverse Reactions in Nephrotic Syndrome Patients.

Current medical science - 1 Oct 2024

Zhai Ya-Ling, Sun Shuai-Gang, Zhang Wen-Hui, Tian Hui-Juan, Zhao Zhan-Zheng

Abstract excerpt

OBJECTIVE: Glucocorticoid (GC)-induced adverse reactions (ARs) have been extensively studied due to their potential impact on patients' health. This study aimed to examine the potential correlation between two polymorphisms [adenosine triphosphate-binding cassette B1 (ABCB1) C3435T and plasminogen activator inhibitor-1 (PAI-1) 4G/5G] and various GC-induced ARs in nephrotic syndrome (NS) patients. METHODS: In this...

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Share to ATP Binding Cassette Transporter, Subfamily B
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Glucocorticoids

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Share to Plasminogen Activator Inhibitor 1

Share to Polymorphism, Single Nucleotide

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PMID: 39285050
DOI: 10.1007/s11596-024-2887-x

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