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Article

Combination analysis of three polymorphisms for predicting the risk for steroid-induced osteonecrosis of the femoral head.

Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association - 1 Jul 2008

Kuribayashi Masaaki, Fujioka Mikihiro, Takahashi Kenji A, Arai Yuji, Hirata Tetsurou, Nakajima Shigeo, Yoshimura Norio, Satomi Yoshiko, Nishino Hoyoku, Kondo Kyoko, Fukushima Wakaba, Hirota Yoshio, Kubo Toshikazu

Abstract excerpt

BACKGROUND: Osteonecrosis of the femoral head (ONF) often develops following corticosteroid administration. We previously investigated the genetic background for the development of corticosteroid-induced ONF and found relations between ONF development and genetic polymorphisms in the ATP binding cassette B1 (ABCB1) gene (C3435T), apolipoprotein B (ApoB) gene (C7623T), and cAMP-response element binding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18696186
DOI: 10.1007/s00776-008-1244-4

Genes

ABCB1

Variants

rs3751845
rs3751845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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