Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A hCXCR1 transgenic mouse model containing a conditional color-switching system for imaging of hCXCL8/IL-8 functions in vivo.

Journal of leukocyte biology - 1 Nov 2007

Zheng Lei, Njauw Ching-Ni, Martins-Green Manuela

Abstract excerpt

To address the functions of human CXCL8 (hCXCL8)/IL-8 through hCXCR1 in vivo, we have developed a humanized, transgenic mouse for hCXCR1. This mouse line is versatile and allows for a variety of functional analyses using bioimaging, including Cre/loxP-mediated, tissue-specific hCXCR1 expression in a spatiotemporal manner; a color-switching mechanism, which uses spectrum-complementary, genetically encoded green...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chemotaxis
Share to Estrogen Antagonists
Share to Integrases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-8

Share to NIH 3T3 Cells

Share to Receptors, Interleukin-8A

Share to Red Fluorescent Protein

Share to Tamoxifen

Source

Identifiers

PMID: 17704296
DOI: 10.1189/jlb.0307141

Genes

CXCL8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A hCXCR1 transgenic mouse model containing a conditional color-switching system for imaging of hCXCL8/IL-8 functions in vivo.PMID 17704296Read ↗

A one-plasmid conditional color-switching transgenic system for multimodal bioimaging.Semantic proximity Read ↗

A pink mouse reports the switch from red to green fluorescence upon Cre-mediated recombination.Semantic proximity Read ↗

Ubiquitous expression of the monomeric red fluorescent protein mCherry in transgenic mice.Semantic proximity Read ↗

Transgenic Targeting of <i>Fcrls</i> Creates a Highly Efficient Constitutively Active Microglia Cre Line with Differentiated SpecificitySemantic proximity Read ↗

STOP floxing around: Specificity and leakiness of inducible Cre/loxP systems.Semantic proximity Read ↗

Analysis of combinatorial chemokine receptor expression dynamics using multi-receptor reporter miceSemantic proximity Read ↗

Generation and characterization of a tamoxifen-inducible, Cre driver rat for transgene expression in microgliaSemantic proximity Read ↗

Generation and characterization of a tamoxifen-inducible, Cre driver rat for transgene expression in microgliaSemantic proximity Read ↗

Analysis of combinatorial chemokine receptor expression dynamics using multi-receptor reporter miceSemantic proximity Read ↗

Human CD68 promoter GFP transgenic mice allow analysis of monocyte to macrophage differentiation in vivo.Semantic proximity Read ↗

Temporally and spatially controlled expression of transgenes in embryonic and adult tissues.Semantic proximity Read ↗

Generation and characterization of mice harboring a conditional CXCL12 allele.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.