Article
A one-plasmid conditional color-switching transgenic system for multimodal bioimaging.
Transgenic research - 1 Aug 2008
Zheng Lei, Njauw Ching-Ni, Martins-Green Manuela
Abstract excerpt
We have developed a new construct to generate transgenic mice with one plasmid that offers: (1) Cre/loxP-mediated spatial and temporally-controlled tissue-specific transgene expression; (2) A color-switching mechanism that uses spectrum-complementary genetically-encoded red (mRFP) and green (eGFP) fluorescent markers to label the transgene-expressing cells; (3) A bioluminescent marker that turns-on in the...
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