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Article

Effects of aneuploidy on cellular physiology and cell division in haploid yeast.

Science (New York, N.Y.) - 17 Aug 2007

Torres Eduardo M, Sokolsky Tanya, Tucker Cheryl M, Chan Leon Y, Boselli Monica, Dunham Maitreya J, Amon Angelika

Abstract excerpt

Aneuploidy is a condition frequently found in tumor cells, but its effect on cellular physiology is not known. We have characterized one aspect of aneuploidy: the gain of extra chromosomes. We created a collection of haploid yeast strains that each bear an extra copy of one or more of almost all of the yeast chromosomes. Their characterization revealed that aneuploid strains share a number of phenotypes,...

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Identifiers

PMID: 17702937
DOI: 10.1126/science.1142210

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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