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Article

Two-stage testing strategies for genome-wide association studies in family-based designs.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

Murphy Amy, T Weiss Scott, Lange Christoph

Abstract excerpt

The analysis of genome-wide association studies (GWAS) poses statistical hurdles that have to be handled efficiently in order for the study to be successful. The two largest impediments in the analysis phase of the study are the multiple comparisons problem and maintaining robustness against confounding due to population admixture and stratification. For quantitative traits in family-based designs, Van Steen (1)...

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PMID: 20652517
DOI: 10.1007/978-1-60761-580-4_17

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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