Article
Association of MMP7 -181A→G Promoter Polymorphism with Gastric Cancer Risk: INFLUENCE OF NICOTINE IN DIFFERENTIAL ALLELE-SPECIFIC TRANSCRIPTION VIA INCREASED PHOSPHORYLATION OF cAMP-RESPONSE ELEMENT-BINDING PROTEIN (CREB).
The Journal of biological chemistry - 5 Jun 2015
Kesh Kousik, Subramanian Lakshmi, Ghosh Nillu, Gupta Vinayak, Gupta Arnab, Bhattacharya Samir, Mahapatra Nitish R, Swarnakar Snehasikta
Abstract excerpt
Elevated expression of matrix metalloproteinase7 (MMP7) has been demonstrated to play a pivotal role in cancer invasion. The -181A→G (rs11568818) polymorphism in the MMP7 promoter modulates gene expression and possibly affects cancer progression. Here, we evaluated the impact of -181A→G polymorph...
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