Article
MMP7 -181G allele is a low-penetrant risk factor for cancer development in East Asians.
DNA and cell biology - 1 May 2012
Yuan-Yuan Mi, Li-Feng Zhang, Li-Jie Zhu
Abstract excerpt
Matrix metalloproteinase-7 (MMP-7) is a small secreted proteolytic enzyme with broad substrate specificity. Its expression is associated with tumor invasion, metastasis, and survival for a number of cancers. However, data from published studies with individually low statistical power are conflicting. Here, we performed a meta-analysis of 14 publications (16 case-control studies) to better assess the purported...
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