Article
A/G Polymorphism of the MMP-7 Gene Promoter Region in Colorectal Cancer.
Polski przeglad chirurgiczny - 1 Nov 2011
Dziki Lukasz, Przybyłowska Karolina, Majsterek Ireneusz, Trzciński Radzisław, Mik Michał, Sygut Andrzej
Abstract excerpt
In gastrointestinal malignancies increased expression of matrilysin - MMP-7 - is often observed. Its high level positively correlates with clinical stage of malignancy and is a negative prognostic factor. This suggests a possible relationship between functional polymorphisms of the MMP-7 gene and susceptibility to development of colorectal cancer and an aggressive course of the disease.The aim of the study was to...
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