Article
Role of the metalloproteinase-7 (181A>G) polymorphism in gastric cancer susceptibility: a case control study in Kashmir valley.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011
Malik Manzoor Ahmad, Zargar Showket Ali, Mittal Balraj
Abstract excerpt
Matrix metalloproteinase-7 (MMP-7) is a small secreted proteolytic enzyme with broad substrate specificity against extracellular matrix (ECM) and non-ECM components. A promoter polymorphism MMP-7 181A>G is known to modify the gene transcription activity of the proteinase gene and influence susceptibility to various cancers. The present case-control study comprising 108 gastric cancer (GC) patients and 195 healthy...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
