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Article

Direct linkage of mitochondrial genome variation to risk factors for type 2 diabetes in conplastic strains.

Genome research - 1 Sept 2007

Pravenec Michal, Hyakukoku Masaya, Houstek Josef, Zidek Vaclav, Landa Vladimir, Mlejnek Petr, Miksik Ivan, Dudová-Mothejzikova Kristyna, Pecina Petr, Vrbacky Marek, Drahota Zdenek, Vojtiskova Alena, Mracek Tomas, Kazdova Ludmila, Oliyarnyk Olena, Wang Jiaming, Ho Christopher, Qi Nathan, Sugimoto Ken, Kurtz Theodore

Abstract excerpt

Recently, the relationship of mitochondrial DNA (mtDNA) variants to metabolic risk factors for diabetes and other common diseases has begun to attract increasing attention. However, progress in this area has been limited because (1) the phenotypic effects of variation in the mitochondrial genome are difficult to isolate owing to confounding variation in the nuclear genome, imprinting phenomena, and environmental...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 17693571
DOI: 10.1101/gr.6548207
PMCID: PMC1950900

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Source receipt: pubmed, retrieved 7 Sept 2026.

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