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Article

Dissecting the effects of mtDNA variations on complex traits using mouse conplastic strains.

Genome research - 1 Jan 2009

Yu Xinhua, Gimsa Ulrike, Wester-Rosenlöf Lena, Kanitz Ellen, Otten Winfried, Kunz Manfred, Ibrahim Saleh M

Abstract excerpt

Previous reports have demonstrated that the mtDNA of mouse common inbred strains (CIS) originated from a single female ancestor and that mtDNA mutations occurred during CIS establishment. This situation provides a unique opportunity to investigate the impact of individual mtDNA variations on complex traits in mammals. In this study, we compiled the complete mtDNA sequences of 52 mouse CIS. Phylogenetic analysis...

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Source

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Identifiers

PMID: 19037013
DOI: 10.1101/gr.078865.108
PMCID: PMC2612955

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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