Article
Construction of two novel reciprocal conplastic rat strains and characterization of cardiac mitochondria.
American journal of physiology. Heart and circulatory physiology - 1 Jan 2013
Kumarasamy Sivarajan, Gopalakrishnan Kathirvel, Abdul-Majeed Shakila, Partow-Navid Rod, Farms Phyllis, Joe Bina
Abstract excerpt
Because of the lack of appropriate animal models, the potentially causal contributions of inherited mitochondrial genomic factors to complex traits are less well studied compared with inherited nuclear genomic factors. We previously detected variations between the mitochondrial DNA (mtDNA) of the Dahl salt-sensitive (S) rat and the spontaneously hypertensive rat (SHR). Specifically, multiple variations were...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
