Article
Functional and phenotypic characterization of peptide-vaccine-induced HCV-specific CD8+ T cells in healthy individuals and chronic hepatitis C patients.
Vaccine - 17 Sept 2007
Schlaphoff Verena, Klade Christoph S, Jilma Bernd, Jelovcan Sandra B, Cornberg Markus, Tauber Erich, Manns Michael P, Wedemeyer Heiner
Abstract excerpt
Only very limited information on phenotype and function of vaccine-induced CD8+ T cells is available for humans. We investigated hepatitis C virus-specific CD8+ T cells after vaccination with the HCV peptide-vaccine IC41 which includes 5 MHC-class I and 3 MHC class-II-restricted epitopes. In heal...
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