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Article

Hepatitis C virus (HCV) sequence variation induces an HCV-specific T-cell phenotype analogous to spontaneous resolution.

Journal of virology - 1 Feb 2010

Kasprowicz Victoria, Kang Yu-Hoi, Lucas Michaela, Schulze zur Wiesch Julian, Kuntzen Thomas, Fleming Vicki, Nolan Brian E, Longworth Steven, Berical Andrew, Bengsch Bertram, Thimme Robert, Lewis-Ximenez Lia, Allen Todd M, Kim Arthur Y, Klenerman Paul, Lauer Georg M

Abstract excerpt

Hepatitis C virus (HCV)-specific CD8(+) T cells in persistent HCV infection are low in frequency and paradoxically show a phenotype associated with controlled infections, expressing the memory marker CD127. We addressed to what extent this phenotype is dependent on the presence of cognate antigen...

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Identifiers

PMID: 19906915
DOI: 10.1128/JVI.01499-09
PMCID: PMC2812309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19906915-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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