Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An epitope in hepatitis C virus core region recognized by cytotoxic T cells in mice and humans

1 May 1994

Abstract excerpt

Several cytotoxic T-lymphocyte (CTL) epitopes have been defined in hepatitis C virus (HCV) proteins. CTL may play an important role in the control of infection by HCV. Here, we identify a highly conserved antigenic site in the HCV core recognized by both murine and human CTL. Spleen cells from mice immunized with a recombinant vaccinia virus expressing the HCV core gene were restimulated in vitro with 11 peptides...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hepatitis B Virus Studies
Share to Hepatitis C virus research
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 7512163
DOI: 10.1128/jvi.68.5.3334-3342.1994

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An epitope in hepatitis C virus core region recognized by cytotoxic T cells in mice and humansPMID 7512163Read ↗

Three new cytotoxic T cell epitopes identified within the hepatitis C virus nucleoprotein.Semantic proximity Read ↗

A new unconventional HLA-A2-restricted epitope from HBV core protein elicits antiviral cytotoxic T lymphocytes.Semantic proximity Read ↗

CTL responses of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1.Semantic proximity Read ↗

HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release.Semantic proximity Read ↗

Core Antigen Mutations of Human Hepatitis B Virus in Hepatomas Accumulate in MHC Class II-Restricted T Cell EpitopesSemantic proximity Read ↗

HCV epitope, homologous to multiple human protein sequences, induces a regulatory T cell response in infected patientsSemantic proximity Read ↗

Rational Design of a Multiepitope Vaccine Encoding T-Lymphocyte Epitopes for Treatment of Chronic Hepatitis B Virus InfectionsSemantic proximity Read ↗

A peptide derived from hepatitis C virus (HCV) core protein inducing cellular responses in patients with HCV with various HLA class IA alleles.Semantic proximity Read ↗

Cytotoxic T lymphocyte response and viral load in hepatitis C virus infection.Semantic proximity Read ↗

Human CD4+ T-cell response to hepatitis delta virus: identification of multiple epitopes and characterization of T-helper cytokine profilesSemantic proximity Read ↗

Generation of cytotoxicity against hepatitis delta virus genotypes and quasispecies by epitope modification.Semantic proximity Read ↗

Minimal T-cell-stimulatory sequences and spectrum of HLA restriction of immunodominant CD4+ T-cell epitopes within hepatitis C virus NS3 and NS4 proteins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.